Publications

  • Papers in scientific journals

    2020

    • Sousa SA, Seixas AMM, Mandal M, Rodríguez-Ortega MJ, Leitão JH. “Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome”. Vaccines (2020), 8(3):E509. https://doi.org/10.3390/vaccines8030509

    • Galán-Relaño Á, Gómez-Gascón L, Rodríguez-Franco A, Luque I, Huerta B, Tarradas C, Rodríguez-Ortega MJ. “Search of Potential Vaccine Candidates against Trueperella pyogenes Infections through Proteomic and Bioinformatic Analysis”. Vaccines (2020), 8(2):E314. https://doi.org/10.3390/vaccines8020314

    • Prados de la Torre E, Rodríguez-Franco A, Rodríguez-Ortega MJ. “Proteomic and Bioinformatic Analysis of Streptococcus suis Human Isolates: Combined Prediction of Potential Vaccine Candidates”. Vaccines (2020), 8(2):E188. https://doi.org/10.3390/vaccines8020188

    2019

    • Izquierdo-González JJ, Amil-Ruiz F, Zazzu S, Sánchez-Lucas R, Fuentes-Almagro CA, Rodríguez-Ortega MJ. “Proteomic analysis of goat milk kefir: Profiling the fermentation-time dependent protein digestion and identification of potential peptides with biological activity”. Food Chemistry (2019), 295:456-465. https://doi.org/10.1016/j.foodchem.2019.05.178

    • Mitsuwan W, Jiménez-Munguía I, Visutthi M, Sianglum W; REIPI/GEIH Study Group, Rodríguez-Ortega MJ, Voravuthikunchai SP. “Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles”. Microbial Pathogenesis (2019), 128:112-118. https://doi.org/10.1016/j.micpath.2018.12.019.

    2018

    • Gómez-Gascón L, Luque I, Tarradas C, Olaya-Abril A, Astorga RJ, Huerta B, Rodríguez-Ortega MJ. “Comparative immunosecretome analysis of prevalent Streptococcus suis serotypes”. Comparative Immunology, Microbiology & Infectious Diseases (2018), 57: 55-61. https://doi.org/10.1016/j.cimid.2018.06.006

    • Jiménez-Munguía I, Calderón-Santiago M, Rodríguez-Franco A, Priego-Capote F, Rodríguez-Ortega MJ. “Multi-omic profiling to assess the effect of iron starvation in Streptococcus pneumoniae TIGR4”. PeerJ (2018), 6:e4966. https://doi.org/10.7717/peerj.4966

    2017

    • Mitsuwan W, Olaya-Abril A, Calderón-Santiago M, Jiménez-Munguía I, González-Reyes JA, Priego-Capote F, Voravuthikunchai SP, Rodríguez-Ortega MJ. “Integrated proteomic and metabolomic analysis reveals that rhodomyrtone reduces the capsule in Streptococcus pneumoniae”. Scientific Reports (2017), 7(1):2715. https://doi.org/ 10.1038/s41598-017-02996-3

    2016

    • Gómez-Gascón L, Cardoso-Toset F, Tarradas C, Gómez-Laguna J, Maldonado A, Nielsen J, Olaya-Abril A, Rodríguez-Ortega MJ, Luque I. “Characterization of the immune response and evaluation of the protective capacity of rSsnA against Streptococcus suis infection in pigs”. Comparative Immunology, Microbiology & Infectious Diseases (2016), 47: 52-59. https://doi.org/ 10.1016/j.cimid.2016.06.001

    • Olaya-Abril A, Obando I, Rodríguez-Ortega MJ. “Data in support of proteomic analysis of pneumococcal pediatric clinical isolates to construct a protein array”. Data in Brief (2016), 6:917-922. https://doi.org/ 10.1016/j.dib.2016.01.057

    2015

    • Olaya-Abril A, Jiménez-Munguía I, Gómez-Gascón L, Obando I, Rodríguez-Ortega MJ. “A Pneumococcal Protein Array as a Platform to Discover Serodiagnostic Antigens Against Infection”. Molecular & Cellular Proteomics (2015), 14(10):2591-2608. https://doi.org/ 10.1074/mcp.M115.049544

    • Jiménez-Munguía I, van Wamel WJ, Olaya-Abril A, García-Cabrera E, Rodríguez-Ortega MJ, Obando I. “Proteomics-driven design of a multiplex bead-based platform to assess natural IgG antibodies to pneumococcal protein antigens in children”. Journal of Proteomics (2015), 126:228-233. https://doi.org/ 10.1016/j.jprot.2015.06.011

    • Jorrín-Novo JV, Pascual J, Sánchez-Lucas R, Romero-Rodríguez MC, Rodríguez-Ortega MJ, Lenz C, Valledor L. “Fourteen years of plant proteomics reflected in Proteomics: moving from model species and 2DE-based approaches to orphan species and gel-free platforms”. Proteomics (2015), 15(5-6):1089-1112. https://doi.org/ 10.1002/pmic.201400349

    2014

    • Gómez-Gascón L, Cardoso-Toset F, Amarilla PS, Tarradas C, Carrasco L, Olaya-Abril A, Jiménez-Munguía I, Rodríguez-Ortega MJ, Luque I. “A new recombinant SsnA protein combined with aluminum hydroxide protects mouse against Streptococcus suis”. Vaccine (2014), 32(51):6992-6999. https://doi.org/ 10.1016/j.vaccine.2014.10.019

    • Olaya-Abril A, Prados-Rosales R, McConnell MJ, Martín-Peña R, González-Reyes JA, Jiménez-Munguía I, Gómez-Gascón L, Fernández J, Luque-García JL, García-Lidón C, Estévez H, Pachón J, Obando I, Casadevall A, Pirofski LA, Rodríguez-Ortega MJ. “Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae”. Journal of Proteomics (2014), 106:46-60. https://doi.org/ 10.1016/j.jprot.2014.04.023

    • Olaya-Abril A, Jiménez-Munguía I, Gómez-Gascón L, Rodríguez-Ortega MJ. “Surfomics: Shaving live organisms for a fast proteomic identification of surface proteins”. Journal of Proteomics (2014), Jan 31; 97:164-176. https://doi.org/ 10.1016/j.jprot.2013.03.035

    2013

    • Olaya-Abril A, Jiménez-Munguía I, Gómez-Gascón L, Obando I, Rodríguez-Ortega MJ. “Identification of potential new protein vaccine candidates through pan-surfomic analysis of pneumococcal clinical isolates from adults”. PLoS One (2013) Jul 23;8(7):e70365. https://doi.org/ 10.1371/journal.pone.0070365

    2012

    • Gómez-Gascón L, Luque I, Olaya-Abril A, Jiménez-Munguía I, Orbegozo-Medina RA, Peralbo E, Tarradas C, Rodríguez-Ortega MJ. “Exploring the pan-surfome of Streptococcus suis: looking for common protein antigens”. Journal of Proteomics (2012), 75 (18): 5654-5666. https://doi.org/ 10.1016/j.jprot.2012.07.025

    • Olaya-Abril A, Gómez-Gascón L, Jiménez-Munguía I, Obando I, Rodríguez-Ortega MJ. “Another turn of the screw of shaving Gram-positive bacteria: optimization of proteomics surface identification in Streptococcus pneumoniae”. Journal of Proteomics (2012), 75 (12): 3733-3746. https://doi.org/ 10.1016/j.jprot.2012.04.037

    2010

    • Mandanici F, Gómez-Gascón L, Garibaldi M, Olaya-Abril A, Luque I, Tarradas C, Mancuso G, Papasergi S, Bárcena JA, Teti G, Beninati C, Rodríguez-Ortega MJ. “A surface protein of Streptococcus suis serotype 2 identified by proteomics protects mice against infection”. Journal of Proteomics (2010), 73 (12): 2365-2369. https://doi.org/ 10.1016/j.jprot.2010.07.009

    • Garibaldi M, Rodríguez-Ortega MJ, Mandanici F, Cardaci A, Midiri A, Papasergi S, Gambadoro O, Cavallari V, Teti G, Beninati C. “Immunoprotective activities of a Streptococcus suis pilus subunit in murine models of infection”. Vaccine (2010), 28 (20): 3609-3616. https://doi.org/ 10.1016/j.vaccine.2010.01.009

    2009

    • Doro F, Liberatori S, Rodríguez-Ortega MJ, Rinaudo CD, Rosini R, Mora M, Scarselli M, Altindis E, D’Aurizio R, Stella M, Margarit I, Maione D, Telford JL, Norais N, Grandi G. “Proteomics as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hyper-virulent strain COH1”. Molecular & Cellular Proteomics (2009), 8 (7): 1728-1737. https://doi.org/ 10.1074/mcp.M800486-MCP200

    • Rodríguez-Ortega MJ, Rodríguez-Ariza A, Gómez-Ariza JL, Muñoz-Serrano A, López-Barea J. “Multivariate discriminant analysis distinguishes metal- from non metal-related biomarker responses in the clam Chamaelea gallina”. Marine Pollution Bulletin (2009), 58 (1): 64-71. https://doi.org/ 10.1016/j.marpolbul.2008.09.006

    2008

    • Rodríguez-Ortega MJ, Luque I, Tarradas C, Bárcena JA. “Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach”. BMC Genomics (2008), 9 (1): 588. https://doi.org/ 10.1186/1471-2164-9-588

    • Berlanda Scorza F, Doro F, Rodríguez-Ortega MJ, Stella M, Liberatori S, Taddei AR, Serino L, Gomes Moriel D, Nesta B, Fontana MR, Spagnuolo A, Pizza M, Norais N, Grandi G. “Proteomic characterization of outer membrane vesicles from the Extraintestinal Pathogenic Escherichia coli ΔtolR IHE3034 mutant”. Molecular & Cellular Proteomics (2008), 7 (3): 473-485. https://doi.org/ 10.1074/mcp.M700295-MCP200

    2006

    • Rodríguez-Ortega MJ, Norais N, Bensi G, Liberatori S, Capo S, Mora M, Scarselli M, Doro F, Ferrari G, Garaguso I, Maggi T, Neumann A, Covre A, Telford JL, Grandi G. “Characterization and identification of vaccine candidate proteins through analysis of group A Streptococcus surface proteome”. Nature Biotechnology (2006), 24(2): 191-197. https://doi.org/ 10.1038/nbt1179

    • Grøsvik BE, Jonnson H, Rodríguez-Ortega MJ, Roepstorff P, Goksøyr A. “CYP1A-immunopositive proteins in bivalves responsive to oxidative stress identified as cytoskeletal and major vault proteins”, Aquatic Toxicology (2006), 79(4): 334-340. https://doi.org/ 10.1016/j.aquatox.2006.07.003

    2003

    • Rodríguez-Ortega MJ, Grøsvik BE, Rodríguez-Ariza A, Goksøyr A, López-Barea J. “Changes in protein expression profiles in bivalve molluscs (Chamaelea gallina) exposed to four model environmental pollutants”, Proteomics (2003), 3(8): 1535-1543. https://doi.org/ 10.1002/pmic.200300491

    • Rodríguez-Ariza A, Rodríguez-Ortega MJ, Marenco JL, Amezcua O, Alhama J, López-Barea J. “Uptake and clearance of PCB congeners in Chamaelea gallina: response of oxidative stress biomarkers”. Comparative Biochemistry and Physiology part C (2003), 134: 57-67. https://doi.org/ 10.1016/s1532-0456(02)00207-7

    • Rodríguez-Ortega MJ, Rodríguez-Ariza A, Amezcua O, López-Barea J. “Mutagenic activation of arylamines by subcellular fractions of Chamaelea gallina clams exposed to environmental pollutants”. Environmental and Molecular Mutagenesis (2003), 41(1): 55-63. https://doi.org/ 10.1002/em.10130

    • Romero-Ruiz A, Amezcua O, Rodríguez-Ortega MJ, Muñoz JL, Alhama J, Rodríguez-Ariza A, Gómez-Ariza JL, López-Barea J. “Oxidative stress biomarkers in bivalves transplanted to the Guadalquivir Estuary after Aznalcóllar spill”. Environmental Toxicology and Chemistry (2003), 22(1): 92-100.

    2002

    • Rodríguez-Ortega MJ, Alhama J, Funes V, Romero-Ruiz A, Rodríguez-Ariza A, López-Barea J. “Biochemical biomarkers of pollution in the clam Chamaelea gallina from South-Spanish littoral”. Environmental Toxicology and Chemistry (2002), 21 (3): 542-549.

  • Books and book chapters

    • Rodríguez-Ortega MJ. “New proteomic strategies to study surface proteins in Gram-positive bacteria: application in vaccines”. New Strides in Biotechnology (2008), 173-181. Ed. Sicania (Messina, Italy).

    • Jiménez-Munguía I, van Wamel WJ, Rodríguez-Ortega MJ, Obando I. “Detection of Natural Antibodies and Serological Diagnosis of Pneumococcal Pneumonia Using a Bead-Based High-Throughput Assay”. Methods in Molecular Biology (2017), 1643:169-177. Ed. Humana Press/Springer Protocols Series (New York, USA).

    • Rodríguez-Ortega MJ. “ ‘Shaving’ live bacterial cells with proteases for proteomic analysis of surface proteins”. Methods in Molecular Biology (2018), 1722: 21-29. Ed. Humana Press/Springer Protocols Series (New York, USA).

    • Olaya-Abril A, Rodríguez-Ortega MJ. “Glass Slide-printed Protein Arrays as a Platform to Discover Serodiagnostic Antigens Against Bacterial Infections”. Methods in Molecular Biology (2021), in press. Ed. Humana Press/Springer Protocols Series (New York, USA).

  • Other publications

    • McDonagh B, Ogueta S, Padilla A, Lasarte G, Rodríguez-Ortega MJ, Bárcena JA. “Detection of redox modified proteins by gel-free proteomics”. Proteómica (2010), 1: 48-49. Ed. Servicio de Publicaciones de la Universidad de Córdoba (Córdoba, Spain).

    • Olaya-Abril A, Gómez-Gascón L, Rodríguez-Ortega MJ. “Preparación de extractos proteicos bacterianos para el análisis de glicoproteínas mediante geles bidimensionales y cromatografías de afinidad”. Proteómica (2010), 5: 108-110. Ed. Servicio de Publicaciones de la Universidad de Córdoba (Córdoba, Spain).

    • Gómez-Gascón L, Olaya-Abril A, Rodríguez-Ortega MJ. “Métodos de enriquecimiento de glicoproteínas bacterianas para su posterior análisis y caracterización mediante espectrometría de masas”. Proteómica (2010), 5: 110-112. Ed. Servicio de Publicaciones de la Universidad de Córdoba (Córdoba, Spain).